MHRN Research Highlights and Findings

The 2019-2025 cycle of the MHRN cooperative agreement includes the following cores and research projects:

• MHRN III Infrastructure: Administrative Core
  • PI Greg Simon (KPWA)
• MHRN III Infrastructure: Methods Core
  • PI Greg Simon (KPWA)
• MHRN III Signature Project: Mindfulness intervention to prevent perinatal depression
  • PI Arne Beck (KPCO)
• MHRN III Pilot Project 1: Stakeholder Perspectives on Implementing Suicide Risk Prediction Models
  • PI Bobbi Jo Yarborough (KPNW)
• MHRN III Pilot Project 2: Outreach to Reduce Depression Treatment Disparities
  • PI Vanessa Simiola (KPHI)
• MHRN III Supplemental Project: Impact of buprenorphine on suicidal behavior
  • PI Greg Simon (KPWA)
• MHRN III Supplemental Project: Mental health impacts of COVID-19
  • PI Rebecca Rossom (HPI)
• MHRN Diversity Supplement: Whose depression are we measuring? Considering the role of place on Black women’s depression outcomes
  • PI Kanetha Wilson (KPGA)
  • Projects supported by the MHRN III Feasibility Pilot Program:
    • PHQ9 Differential Item Functioning
      • PI Melissa Harry (EIRH)
    • Using NLP to Increase Identification of Child Maltreatment in EHR
      • PI Rob Penfold (KPWA)
    • COVID-19 Vaccine Uptake and Psychiatric Disorders
      • PI Ashli Owen-Smith (KPGA)
    • Weight Loss and Perinatal Depression
      • Co-PIs Megan Ferber and Kara Christopher (SLU)
    • Implementing Predictive Models for Identifying Suicide Risk in Adolescents
      • PI Julie Richards (KPWA)
    • Trauma and PTSD in Medical Records
      • PI Vanessa Simiola (KPHI)
    • INSPIRED: INtegrating Social determinants and Policy In REducing Disparities
      • PI Yunyu Xiao (Cornell)

Listed below are research projects affiliated with MHRN or supported by MHRN supplemental funding.

• MHRN Post-Doctoral Fellowship
  • PI Brian Ahmedani (HFHS)
• Evaluation of health system Zero Suicide programs
  • PI Brian Ahmedani (HFHS)
• Telehealth: Assessing Services in Kaiser Permanente (TASK)
  • co-PIs Greg Clarke (KPNW) and Rob Penfold (KPWA)
• Pragmatic Trial of Stepped Care for Adolescent Suicide Prevention (Youth SPOT)
  • PI Greg Clarke (KPNW)
• Effects of Medical Products on Suicidal Ideation and Behavior
  • PI Greg Simon (KPWA)
• Improved tailoring of depression care using customized clinical decision support
  • PI Susan Shortreed (KPWA)
• Reduce Racial/Ethnic Disparities in Suicide Risk Prediction (RED)
  • PI Yates Coley (KPWA)
• Syncing Screening and Services for Suicide Prevention across Health and Justice Systems
  • MHRN PI Brian Ahmedani (HFHS)
• Evaluating Effectiveness and Implementation of a Risk Model for Suicide Prevention Across Health Systems
  • PI Bobbi Jo Yarborough (KPNW)
• STAR Caregivers – Virtual Training and Follow-up
  • PI Rob Penfold (KPWA)
• Assisted Identification and Navigation of Early Mental Health Symptoms in Youth
  • PI Rob Penfold (KPWA)
• Improving Suicide Risk Prediction using Social Determinants Data
  • PI Rob Penfold (KPWA)
• Treatment Initiation for New Episodes of Depression in Pregnant Women
  • PI Kristin Palmsten (HPI)
• Pathways from Chronic Prescription Opioid Use to New Onset Mood Disorder
  • PI Jeffrey Scherrer (St. Louis University)
• Trans-America Consortium of the All of Us Research Program
  • co-PIs Brian Ahmedani and Christine Johnson (HFHS)
• Optimizing Care to Prevent Diabetes and Promote Cardiovascular Health Among Younger Adults with Severe Mental Illness
  • PI Esti Iturralde (KPNC)
• Employing a stepped-wedge design to implement an evidence-based psychotherapy for PTSD in six large diverse health systems
  • co-PIs Vanessa Simiola (KPHI) and Joan Cook (Yale)
• Optimizing Firearm Suicide Prevention in Healthcare
  • PI Julie Richards (KPWA)
• A comparative effectiveness trial of strategies to implement firearm safety promotion as a universal suicide prevention strategy in pediatric primary care (ASPIRE)
  • PI Rinad Beidas (UPenn)
• Pilot Testing Implementation of Suicide Risk Prediction Algorithms to Support Suicide Prevention in Primary Care
  • PI Julie Richards (KPWA)
• Computational Strategies to Tailor Existing Interventions for First Major Depressive Episodes to Inform and Test Personalized Interventions
  • PI Kathryn Erickson-Ridout (KPNC)
• Understanding Structural Social Determinants of Suicidal Trajectories
  • PI Yunyu Xiao (Cornell)
• Autism Registry
  • PI: Lisa Croen (KPNC)
• Automated Virtual Follow-Up to Reduce Premature Treatment Discontinuation
  • PI: Robert Penfold (KPWA)
• Behavioral Activation for Perinatal Depression
  • PI: Arne Beck (KPCO)
• Building Capacity for Stakeholder Engagement in the MHRN
  • PI: Karen Coleman (KPSC)
• Care of Mental, Physical and Substance Use Syndromes (COMPASS)
  • PI: Sanne Magnan (HPI)
• Comparative Risks and Benefits of Gender Reassignment Therapies
  • PI: Michael Goodman (Emory University)
• Computational Modeling of Suicide Risk
  • PI: Gregory Simon (KPWA)
• Developing Tools to Evaluate the Impact of Safety Planning and Lethal Means Assessment on Suicide Outcomes
  • PI: Brian Ahmedani (HFHS)
• Diversity Supplement – Understanding factors that lead to disparities in depression treatment
  • PI: Karen J Coleman (KPSC)
• Effectiveness of Task Shifting to Peer Delivery of Behavioral Activation for Depression among Pregnant Women
  • PI: Sona Dimidjian (University of Colorado)
• Evaluating the Impact of Changes in Opioid Prescribing across Health Systems Implementing Zero Suicide
  • PI: Brian Ahmedani (HFHS)
• FDA Black Box Warning and Suicide
  • PI: Stephen Soumerai (HPHC)
• Firearms means restriction for suicide prevention in pediatric primary care
  • PI: Rinad Beidas (University of Pennsylvania)
• Maximizing Biospecimen Collection for Childhood Disorders
  • PI: Lisa Croen (KPNC)
• Mindfulness-based cognitive therapy for prevention of perinatal depression
  • PI: Sona Dimidjian (University of Colorado)
• Next Generation Assessment Using Mobile Devices
  • PI: Gregory Clarke (KPNW)
• Predictive Modeling: The Role of Opioid Use in Suicide Risk
  • PI: Bobbi Jo Yarborough (KPNW)
• Practice Variation in High- and Low-value Care for Mood Disorders
  • PI: Gregory Simon (KPWA)
• Pragmatic Trial of Population-based Programs to Prevent Suicide Attempt
  • PI: Greg Simon (KPWA)
• Precursors of first-episode psychosis in a population-based sample
  • PI: Gregory Simon (KPWA)
• Reducing Excess Cardiovascular Risk in People with Serious Mental Illness
  • PI: Rebecca Rossom (HPI)
• Safer Use of Antipsychotics in Youth (SUAY)
  • PI: Robert Penfold (KPWA)
• Suicide Supplement: Development of a Population-Based Risk Calculator for Suicidal Behavior
  • PI: Greg Simon (KPWA)
• Treatment Utilization Before Suicide
  • PI: Brian Ahmedani (HFHS)